Effect of serving size and addition of sugar on the glycemic response elicited by oatmeal: A randomized, cross-over study

Clin Nutr ESPEN. 2016 Dec:16:48-54. doi: 10.1016/j.clnesp.2016.07.003. Epub 2016 Sep 1.

Abstract

Background & aims: We aimed to determine the impact of serving size and addition of sucrose on the glycemic response elicited by oatmeal.

Methods: We studied 38 healthy subjects (mean ± SD age 40 ± 12 yr, BMI 26.4 ± 3.6 kg/m2) on 8 separate days using a randomized, cross-over design. Capillary blood-glucose responses over 2hr after consuming 30, 40 and 60 g Classic Quaker Quick Oats (18, 24 and 36 g available-carbohydrate [avCHO], respectively) and 30 g Oats plus 9 g sucrose (27 g avCHO) were compared with those after avCHO-matched servings of Cream of Rice cereal (Control) (22, 29, 44 and 33 g cereal, respectively). Blood-glucose incremental area under the curve (iAUC), peak-rise, rate-of-decline, time-to-peak and time-to-baseline were calculated.

Results: As serving size increased, iAUC, peak-rise, rate-of-decline and time-to-baseline increased significantly for both cereals, but the rate of increase was significantly greater for Control than for Oats. Time-to-peak increased significantly with serving size only for Oats. Compared to avCHO-matched servings of Control, mean (95%CI) iAUC, peak-rise and rate-of-decline, respectively were 22 (16, 27)%, 22 (19, 26)% and 23 (18, 27)% lower after consuming Oats without sucrose and 26 (18, 34)%, 14 (9, 20)% and 16 (9, 24)% lower after consuming Oats plus sucrose.

Conclusions: Oatmeal elicited a significantly lower glycemic response than avCHO-matched servings of Cream of Rice, even when sucrose was added to the oatmeal. Measures of glycemic response tended to increase with increased serving size; although the pattern of change varied between cereal types. These results suggest that oatmeal may be a good choice for minimizing postprandial glycemia.

Clinical trial registry: ClinicalTrials.gov (NCT02506972).

Keywords: Beta-glucan; Breakfast; Humans; Oats; Postprandial blood glucose; Sucrose; Sugar.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Area Under Curve
  • Avena
  • Blood Glucose / analysis*
  • Breakfast
  • Cross-Over Studies
  • Diet
  • Dietary Carbohydrates / administration & dosage
  • Dietary Carbohydrates / blood
  • Dietary Carbohydrates / pharmacology*
  • Edible Grain / chemistry*
  • Female
  • Glycemic Index
  • Humans
  • Male
  • Middle Aged
  • Oryza
  • Postprandial Period
  • Probability
  • Serving Size*
  • Sucrose
  • Sugars / administration & dosage*
  • Young Adult
  • beta-Glucans / chemistry
  • beta-Glucans / pharmacology

Substances

  • Blood Glucose
  • Dietary Carbohydrates
  • Sugars
  • beta-Glucans
  • Sucrose

Associated data

  • ClinicalTrials.gov/NCT02506972