The Pathogenic Transforming Growth Factor-β Overdrive Hypothesis in Aortic Aneurysms and Dissections: A Mirage?

Circ Res. 2017 May 26;120(11):1718-1720. doi: 10.1161/CIRCRESAHA.116.310371.
No abstract available

Keywords: aneurysm; aorta; aortic dissection; connective tissue; extracellular matrix; losartan.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Aortic Aneurysm / genetics
  • Aortic Aneurysm / metabolism*
  • Aortic Dissection / genetics
  • Aortic Dissection / metabolism*
  • Humans
  • Marfan Syndrome / genetics
  • Marfan Syndrome / metabolism
  • Mutation / physiology*
  • Transforming Growth Factor beta / genetics
  • Transforming Growth Factor beta / metabolism*

Substances

  • Transforming Growth Factor beta