[Impact of pharmaceutical interventions on antibiotic therapy of urinary tract infections in rehabilitation center]

Prog Urol. 2017 Jun;27(7):439-445. doi: 10.1016/j.purol.2017.04.007. Epub 2017 May 31.
[Article in French]

Abstract

Background: The aim of this study was to assess the impact of medico-pharmaceutical partnership on the quality of antibiotic treatment in urinary tract infection (UTI) within rehabilitation center.

Material: All antibiotic prescriptions were validated by the pharmacist at the start of treatment and twice a week. All patients with symptomatic urinary tract infection between January 1, 2014 to December 31, 2015 were included in this study. Addition to awareness among specifiers to promoting the appropriate use of antibiotics, the pharmacist suggested pharmaceutical interventions (PI) in order to improve the quality of antibiotic treatments. At the same time, 3 quality indicators (QI) were followed: duration, dosage, antibiotic susceptibility. The compliance rates of this 3 QI allowed to assess the quality of the antibiotic treatment in urinary tract infection.

Results: The study population included 154 patients corresponding to 252 UTI. Sixty-eight PI were made by pharmacist about urinary tract infection treatment (overdosage or under-dosing, duration unknown, inadequate route of administration). These QI achieved 96.4% compliance with duration, 98.8% compliance with dosage and 99.2% with the antibiotic susceptibility.

Conclusion: This study allowed showing the medico-pharmaceutical impact on the quality of antibiotic treatments in UTI. The awareness among specifiers with a daily validation of prescription by the pharmacist allowed to improve urinary tract infections care in rehabilitation center.

Level of evidence: 4.

Keywords: Antibiotic; Antibiotique; Indicateur qualité; Infection urinaire; Quality indicator; Rehabilitation center; Urinary tract infection; Établissement de soins de suite et de réadaptation.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use*
  • Drug Prescriptions / statistics & numerical data
  • Drug Utilization / statistics & numerical data
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Rehabilitation Centers
  • Urinary Tract Infections / drug therapy*
  • Young Adult

Substances

  • Anti-Bacterial Agents