Treatment of patients with aortic disease during pregnancy and after delivery

J Int Med Res. 2017 Aug;45(4):1359-1368. doi: 10.1177/0300060517711088. Epub 2017 Jun 6.

Abstract

Objective This study aimed to review treatment of patients with aortic disease during pregnancy and after delivery in Beijing Anzhen Hospital. Methods A retrospective study was conducted using data from 12 patients with aortic disease during pregnancy and after delivery in our institution from May 2005 to December 2014. Patients were provided different treatments based on the type of aortic disease and clinical characteristics. Results The mean age was 29.83 ± 4.17 years, mean height was 171.7 ± 8.22 cm, mean weight was 68.55 ± 10.62 kg, and mean body mass index was 23.18 ± 2.93 kg/m2. Two patients with Stanford type A aortic dissection died of renal failure after surgery. All of the other patients were discharged. Six foetuses survived. One patient continued her pregnancy after an aortic operation. The gestational age of the remaining five patients was less than 28 weeks at the time of the operation and all foetuses of these five patients died. Conclusions A suitable treatment strategy for aortic disease during pregnancy and after delivery should be chosen based on an individual's comprehensive clinical condition. Foetal management should be chosen based on gestational age and severity of aortic disease.

Keywords: Pregnant patient; aortic disease; delivery; pregnancy; treatment.

MeSH terms

  • Adult
  • Aortic Aneurysm / diagnostic imaging
  • Aortic Aneurysm / therapy*
  • Aortic Dissection / diagnostic imaging
  • Aortic Dissection / therapy*
  • Female
  • Humans
  • Postnatal Care
  • Pregnancy
  • Pregnancy Outcome
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult