Lupus in the far east: a modern epidemic

Int J Rheum Dis. 2017 May;20(5):523-525. doi: 10.1111/1756-185X.13115. Epub 2017 Jun 8.

Abstract

Systemic lupus erythematosus (SLE) is a diverse and heterogeneous disease with much variation between different ethnicities. Although more severe and prevalent in non-Caucasian populations, the bulk of evidence regarding 'Asian lupus' had traditionally been extrapolated from studies on patient minorities in the West. Lupus research in Asia has since grown exponentially and now takes a leading role in improving the care for SLE patients worldwide. With recent advances, particularly from studies in population-specific phenotyping, genome-wide association studies, lupus nephritis and innovative treatment modalities, we now have an expanding understanding of both the basic science and clinical management of SLE. Upcoming breakthroughs from growing multi-ethnic cohorts and international collaborations will likely bring further important ramifications for SLE management in the near future.

Keywords: Epidemiology < Systemic lupus erythematosus; Systemic lupus erythematosus.

Publication types

  • Review

MeSH terms

  • Asia / epidemiology
  • Asian People*
  • Epidemics*
  • Humans
  • Lupus Erythematosus, Systemic / diagnosis
  • Lupus Erythematosus, Systemic / ethnology*
  • Lupus Erythematosus, Systemic / therapy
  • Prognosis
  • Risk Factors