Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxin-producing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017

Euro Surveill. 2017 May 25;22(21):30541. doi: 10.2807/1560-7917.ES.2017.22.21.30541.

Abstract

We report an ongoing, protracted and geographically dispersed outbreak of haemolytic uraemic syndrome (HUS) and gastroenteritis in Germany, involving 30 cases since December 2016. The outbreak was caused by the sorbitol-fermenting immotile variant of Shiga toxin-producing (STEC) Escherichia coli O157. Molecular typing revealed close relatedness between isolates from 14 cases. One HUS patient died. Results of a case-control study suggest packaged minced meat as the most likely food vehicle. Food safety investigations are ongoing.

Keywords: HUS; Shiga toxin-producing E. coli - STEC; food-borne infections; haemolytic uraemic syndrome; outbreak.

MeSH terms

  • Case-Control Studies
  • Child
  • Child, Preschool
  • Disease Outbreaks*
  • Electrophoresis, Gel, Pulsed-Field
  • Escherichia coli Infections / complications*
  • Escherichia coli Infections / epidemiology*
  • Escherichia coli O157 / genetics
  • Escherichia coli O157 / isolation & purification*
  • Escherichia coli O157 / pathogenicity
  • Female
  • Gastroenteritis / complications
  • Gastroenteritis / epidemiology
  • Gastroenteritis / microbiology*
  • Germany / epidemiology
  • Hemolytic-Uremic Syndrome / complications
  • Hemolytic-Uremic Syndrome / epidemiology
  • Hemolytic-Uremic Syndrome / microbiology*
  • Humans
  • Infant
  • Infant, Newborn
  • Meat / microbiology*
  • Serotyping
  • Shiga-Toxigenic Escherichia coli / genetics
  • Shiga-Toxigenic Escherichia coli / isolation & purification
  • Shiga-Toxigenic Escherichia coli / pathogenicity
  • Sorbitol
  • Whole Genome Sequencing

Substances

  • Sorbitol