Periodontal status of candidates for allogeneic hematopoietic stem cell transplantation

Spec Care Dentist. 2017 Jul;37(4):187-193. doi: 10.1111/scd.12229. Epub 2017 Jun 12.

Abstract

Purpose: The aim of this study was to describe the periodontal profile of -candidates for allogeneic hematopoietic stem cell transplantation.

Methods: This cross-sectional prospective study was performed from March 2014 to March 2015. After an initial interview, eligible individuals were evaluated by the following clinical parameters: visible plaque, bleeding on probing, probing depth, and clinical attachment level at six sites per tooth, excluding third molars.

Results: Thirty-six candidates for allogeneic hematopoietic stem cell transplantation (HSCT) were clinically assessed. Eight (22%) patients were diagnosed with gingivitis and 21 (58%) of them with periodontitis. The gingival bleeding was statistically correlated with the percentage of sites with visible plaque (p < 0.0001; r = 0.630) and did not correlate with the number of platelets (p = 0.643, r = -0.082).

Conclusions: The candidates for allogeneic HSCT studied showed a high prevalence of periodontal diseases with unmonitored local infection before transplantation.

Keywords: dental; dental care; hematopoietic stem cell transplantation; infection control; periodontal diseases; supportive care.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brazil / epidemiology
  • Cross-Sectional Studies
  • Female
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Male
  • Middle Aged
  • Periodontal Diseases / epidemiology*
  • Periodontal Index
  • Prevalence
  • Prospective Studies
  • Surveys and Questionnaires