Unconventional Interrogation Yields HIV's Escape Plan

Thomas B Kepler

doi:10.1016/j.chom.2017.06.003

Unconventional Interrogation Yields HIV's Escape Plan

Cell Host Microbe. 2017 Jun 14;21(6):659-660. doi: 10.1016/j.chom.2017.06.003.

Author

Thomas B Kepler¹

Affiliation

¹ Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address: [email protected].

PMID: 28618264
DOI: 10.1016/j.chom.2017.06.003

Abstract

Chasing HIV-1 across the genotype landscape, unequipped to anticipate its maneuvers, the antibody variable-region genes pursue the virus in futility. In this issue of Cell Host & Microbe, Dingens et al. (2017) exhibit a powerful technology that reveals the escape pathways of HIV-1 and may enable its capture.

MeSH terms

Adaptation, Biological / immunology
Antibodies, Viral
Genotype*
HIV Infections / immunology*
HIV Infections / virology
HIV-1 / genetics*
HIV-1 / immunology*
Host-Pathogen Interactions / immunology
Humans
Mutation

Substances

Antibodies, Viral