Three new oleanane-type triterpenoid saponins from the seeds of Celosia cristata L

Nat Prod Res. 2018 Jan;32(2):167-174. doi: 10.1080/14786419.2017.1343317. Epub 2017 Jun 28.

Abstract

Phytochemical investigation of the 1-butanol soluble fraction of 60% ethanol extract of the seeds of Celosia cristata L. led to the identification of three new oleanane-type triterpenoid saponins. Using 1D and 2D NMR experiment methods, ESI-MS analysis and acid hydrolysis, their structures were identified as 3-O-[β-D-xylopyranosyl-(1 → 3)-β-D-glucuronopyranosyl]-2β-hydroxy-oleanolic acid-28-O-β-D-glucopyranoside (1), 3-O-[β-D-xylopyranosyl-(1 → 3)-β-D-glucuronopyranosyl]-2β, 23-dihydroxy-oleanolic acid-28-O-β-D-glucopyranoside (2) and 3-O-[β-D-glucopyranosyl-(1 → 4)-β-D-glucopyranosyl]-2-hydroxyl-medicagenic acid-28-O-β-D-glucopyranosyide (3), respectively.

Keywords: Celosia cristata; chemical constituent; triterpenoid saponin.

MeSH terms

  • Carbohydrate Conformation
  • Carbohydrate Sequence
  • Celosia / chemistry*
  • Hydrolysis
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification*
  • Saponins / chemistry
  • Saponins / isolation & purification*
  • Seeds / chemistry

Substances

  • Saponins
  • oleanane
  • Oleanolic Acid