The method of the implant fixation for prophylaxis of complications after alloplasty of complex abdominal wall defects was proposed. Taking into account physico-mechan- ical parameters of implant, degree of anisotropy, in accordance to mechanical and morphological characteristics of the abdominal wall musculo-aponeurotic structures, it is possible to individualize the choice maximally, to plan the alloplasty kind, and to determine the method of optimal surgical treatment objectively.