Improvement in Right Ventricular Strain with Ambrisentan and Tadalafil Upfront Therapy in Scleroderma-associated Pulmonary Arterial Hypertension

Am J Respir Crit Care Med. 2018 Feb 1;197(3):388-391. doi: 10.1164/rccm.201704-0789LE.
No abstract available

Publication types

  • Controlled Clinical Trial
  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cohort Studies
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • Humans
  • Hypertension, Pulmonary / drug therapy*
  • Hypertension, Pulmonary / etiology*
  • Hypertension, Pulmonary / physiopathology
  • Magnetic Resonance Imaging, Cine / methods
  • Male
  • Middle Aged
  • Myocardial Contraction / drug effects
  • Observer Variation
  • Phenylpropionates / therapeutic use*
  • Prospective Studies
  • Pyridazines / therapeutic use*
  • Scleroderma, Limited / complications*
  • Scleroderma, Limited / diagnosis
  • Tadalafil / therapeutic use*
  • Treatment Outcome
  • Ventricular Dysfunction, Right / diagnostic imaging*
  • Ventricular Dysfunction, Right / prevention & control

Substances

  • Phenylpropionates
  • Pyridazines
  • Tadalafil
  • ambrisentan