In Europe, enterovirus A71 (EV-A71) has primarily been associated with sporadic cases of neurological disease. The recent emergence of new genotypes and larger outbreaks with severely ill patients demonstrates a potential for the spread of new, highly pathogenic EV-A71 strains. Detection and characterisation of these new emerging EV variants is challenging as standard EV assays may not be adequate, necessitating the use of whole genome analysis.
Keywords: EV-A71; WGS, NGS, next generation sequencing; enterovirus, classification, Diagnostics, whole genome sequencing.
This article is copyright of The Authors, 2017.