Punctate Radiation Dermatitis of the Foot and Ankle Caused by Distal Embolization of 90Y Microspheres During Liver Directed Therapy

Clin Nucl Med. 2017 Sep;42(9):e422-e423. doi: 10.1097/RLU.0000000000001751.

Abstract

A 41-year-old man with gastric adenocarcinoma presented with hepatic metastases. The metastases were refractory to systemic chemotherapy, so radioembolization with Y microspheres was performed. Because of stasis or saturation of the tumor with embolic particles, 79% of the microspheres were injected. At follow-up, the patient complained of "red bumps" that had developed on his right foot/ankle the day after the radioembolization. Because a portion of the dose was still in the catheter when withdrawn from the right femoral artery, the interventional radiologist used a Geiger counter to confirm radioactivity in the cutaneous lesions and thus the distal embolization of the microspheres.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / pathology
  • Adult
  • Ankle / radiation effects*
  • Dermatitis / etiology*
  • Embolization, Therapeutic / adverse effects*
  • Foot / radiation effects*
  • Humans
  • Liver Neoplasms / radiotherapy
  • Liver Neoplasms / secondary
  • Male
  • Microspheres*
  • Radiation Injuries / etiology*
  • Radiometry
  • Stomach Neoplasms / pathology
  • Yttrium Radioisotopes / adverse effects*
  • Yttrium Radioisotopes / therapeutic use

Substances

  • Yttrium Radioisotopes