A new hereditary colorectal cancer network in the Middle East and eastern mediterranean countries to improve care for high-risk families

Fam Cancer. 2018 Apr;17(2):209-212. doi: 10.1007/s10689-017-0018-6.

Abstract

Colorectal cancer (CRC) has a very high incidence in the western world. Data from registries in the Middle East showed that the incidence of CRC is relatively low in these countries. However, these data also showed that CRC incidence has increased substantially over the past three decades and that a high proportion of cases are diagnosed at an early age (<50 years). In view of these findings, more attention should be paid to prevention. Because of the often limited financial resources, focused screening of individuals with hereditary CRC, in particular those with Lynch syndrome, appears to be the most cost-effective strategy. During recent meetings of the Palestinian Society of Gastroenterology and the Mediterranean Task force for Cancer Control (MTCC) in Jericho, and the Patient's Friends Society of Jerusalem in Hebron the issue of hereditary CRC in the Middle East was discussed and the idea was conceived to establish a network on hereditary colorectal cancer (HCCN-ME) with the goal of improving care for high-risk groups in the Middle East and (Eastern) Mediterranean Countries.

Keywords: CMMRD; Familial colorectal cancer; Health care; Identification; Lynch syndrome; Registry.

MeSH terms

  • Adult
  • Age of Onset
  • Colonoscopy
  • Colorectal Neoplasms, Hereditary Nonpolyposis / diagnosis*
  • Colorectal Neoplasms, Hereditary Nonpolyposis / epidemiology
  • Colorectal Neoplasms, Hereditary Nonpolyposis / genetics
  • Colorectal Neoplasms, Hereditary Nonpolyposis / prevention & control
  • DNA Mismatch Repair / genetics
  • Early Detection of Cancer / economics
  • Early Detection of Cancer / methods*
  • Genetic Predisposition to Disease*
  • Genetic Testing / economics
  • Genetic Testing / methods
  • High-Throughput Nucleotide Sequencing / economics
  • Humans
  • Incidence
  • Mediterranean Region / epidemiology
  • Middle Aged
  • Middle East / epidemiology
  • Quality Improvement / organization & administration*
  • Registries / statistics & numerical data