IgG subclass deficiencies in children: Facts and fiction

Volker Wahn; Horst von Bernuth

doi:10.1111/pai.12757

IgG subclass deficiencies in children: Facts and fiction

Pediatr Allergy Immunol. 2017 Sep;28(6):521-524. doi: 10.1111/pai.12757. Epub 2017 Aug 7.

Authors

Volker Wahn¹, Horst von Bernuth^{1

2

3

4}

Affiliations

¹ Department of Pediatric Pneumology, Immunology and Intensive Care Medicine, Charité University Medicine, Berlin, Germany.
² Department of Immunology, Labor Berlin GmbH, Berlin, Germany.
³ Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
⁴ Center of Social Pediatrics, Charité University Medicine, Berlin, Germany.

PMID: 28686792
DOI: 10.1111/pai.12757

Abstract

The chance to analyse the four IgG subclasses arose with the publication of Terry and Fahey¹ . Since then, a lot of new information on the role of subclasses and their deficiency states in humans has been obtained. This review tries to analyse critically our current knowledge of subclass deficiencies in children.

Keywords: IgG replacement; IgG subclass deficiency; IgG subclasses; children.

Publication types

Review

MeSH terms

Child
Humans
IgG Deficiency / classification
IgG Deficiency / diagnosis*
IgG Deficiency / drug therapy
IgG Deficiency / immunology
Immunoglobulin G / therapeutic use
Immunologic Factors / therapeutic use

Substances

Immunoglobulin G
Immunologic Factors