Abstract
Urinary enzyme excretion was studied in 56 patients treated with cephalosporins in order to evaluate their potential nephrotoxicity. Only in 4 out of 56 patients (7%) was increased NAG, gamma-GT, AlP excretion seen. A rapid return to normal values was observed just after the end of the therapy.
MeSH terms
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Acetylglucosaminidase / urine
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Adolescent
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Adult
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Aged
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Alkaline Phosphatase / urine
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Cefotaxime / adverse effects
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Cefotaxime / analogs & derivatives
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Cefotetan
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Cefotiam
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Cefoxitin / adverse effects
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Ceftriaxone / adverse effects
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Cephalosporins / adverse effects*
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Cephamycins / adverse effects
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Cephradine / adverse effects
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Cephradine / analogs & derivatives
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Child
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Enzymes / urine*
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Female
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Humans
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Kidney / drug effects*
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Male
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Middle Aged
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gamma-Glutamyltransferase / urine
Substances
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Cephalosporins
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Cephamycins
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Enzymes
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Cefotetan
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Cefoxitin
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Ceftriaxone
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Cefotiam
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cefroxadine
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gamma-Glutamyltransferase
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Alkaline Phosphatase
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Acetylglucosaminidase
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Cephradine
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Cefotaxime