Efficacy and safety of a coagulated thrombus injection for peripheral artery perforation: The coagulated thrombus hemostasis method

Catheter Cardiovasc Interv. 2018 Feb 1;91(2):302-307. doi: 10.1002/ccd.27163. Epub 2017 Jul 14.

Abstract

Background: This retrospective study assesses the safety and efficacy of using a thrombus injection for treatment a peripheral artery perforation.

Methods and results: From March 2013 to April 2016, we performed 1,152 endovascular treatment (EVT) at our hospital. Of these, 28 peripheral artery perforations occurred during the EVT procedure and 20 were treated with a thrombus, which we artificially created. The thrombus comprised the patient's blood and thrombin. It was injected into the perforation site from the tip of an over-the-wire balloon using ballooning method. The perforated arteries occurred in below-the-knee artery (45%), superficial femoral artery (35%), deep femoral artery (10%), popliteal artery (5%), and external iliac artery (5%). Thrombus injection was successful in 19 of the 20 perforations (95%). One patient required coil embolization. There were no complications during or after admission.

Conclusions: Thrombus injection is a safety method and might be considered as one of the approaches for stopping peripheral artery perforation.

Keywords: hemostasis; peripheral artery perforation; thrombus.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Arteries / diagnostic imaging
  • Arteries / injuries*
  • Blood Coagulation*
  • Endovascular Procedures / adverse effects*
  • Female
  • Hemorrhage / blood
  • Hemorrhage / diagnostic imaging
  • Hemorrhage / prevention & control*
  • Hemostatic Techniques* / adverse effects
  • Humans
  • Injections, Intra-Arterial
  • Lower Extremity / blood supply*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Thrombosis / blood*
  • Treatment Outcome
  • Vascular System Injuries / blood
  • Vascular System Injuries / diagnostic imaging
  • Vascular System Injuries / therapy*