Diagnostic yield of percutaneous biopsy for sclerotic bone lesions: Influence of mean Hounsfield units

Clin Imaging. 2017 Nov-Dec:46:53-56. doi: 10.1016/j.clinimag.2017.06.008. Epub 2017 Jul 4.

Abstract

Purpose: To identify whether there was an association between Hounsfield units of sclerotic bone lesions and diagnostic yield of biopsy.

Method: All core needle biopsies of sclerotic bone lesion were identified from a database. Pathology reports were reviewed to determine whether the biopsy was diagnostic or non-diagnostic.

Results: 91 patients were included in the study group. The yield for lesions with mean HU≥500 was significantly lower than those with a mean HU≤500 (40% vs. 69.6%, p<0.05).

Conclusion: Lesions with a mean HU>500 are more likely to have a non-diagnostic biopsy than a diagnostic biopsy.

Keywords: Bone biopsy; Computed tomography; Diagnostic yield; Hounsfield units; Sclerotic bone lesions.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Biopsy, Large-Core Needle
  • Bone Diseases / diagnosis
  • Bone Diseases / pathology*
  • Bone and Bones / pathology*
  • Databases, Factual
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed
  • Young Adult