Adenoid cystic carcinoma of the lacrimal gland in a 14-year-old male

Orbit. 2017 Dec;36(6):448-451. doi: 10.1080/01676830.2017.1337187. Epub 2017 Jul 24.

Abstract

Adenoid cystic carcinoma (ACC) of the lacrimal gland is an aggressive, malignant epithelial neoplasm. This tumor is rarely seen in adults and even less commonly seen in children and adolescents; thus, there have been no large studies to date describing the optimal treatment of this malignancy in the pediatric population. Here, we report a case of lacrimal gland ACC in a 14-year-old male treated with neoadjuvant intra-arterial chemotherapy followed by globe-sparing tumor resection and chemoradiation. At 2-year follow-up, he remains disease free without evidence of tumor recurrence.

Keywords: Adenoid cystic carcinoma; intra-arterial chemotherapy; lacrimal gland; pediatric.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Adenoid Cystic / diagnostic imaging
  • Carcinoma, Adenoid Cystic / pathology*
  • Carcinoma, Adenoid Cystic / therapy
  • Chemoradiotherapy
  • Combined Modality Therapy
  • Eye Neoplasms / diagnostic imaging
  • Eye Neoplasms / pathology*
  • Eye Neoplasms / therapy
  • Humans
  • Infusions, Intra-Arterial
  • Lacrimal Apparatus Diseases / diagnostic imaging
  • Lacrimal Apparatus Diseases / pathology*
  • Lacrimal Apparatus Diseases / therapy
  • Magnetic Resonance Imaging
  • Male
  • Neoadjuvant Therapy
  • Ophthalmologic Surgical Procedures
  • Positron-Emission Tomography