Well-defined magnetic surface imprinted nanoparticles for selective enrichment of 2,4-dichlorophenoxyacetic acid in real samples

Le Sheng; Yulong Jin; Yonghuan He; Yanyan Huang; Liushui Yan; Rui Zhao

doi:10.1016/j.talanta.2017.07.002

Well-defined magnetic surface imprinted nanoparticles for selective enrichment of 2,4-dichlorophenoxyacetic acid in real samples

Talanta. 2017 Nov 1:174:725-732. doi: 10.1016/j.talanta.2017.07.002. Epub 2017 Jul 3.

Authors

Le Sheng¹, Yulong Jin², Yonghuan He³, Yanyan Huang³, Liushui Yan⁴, Rui Zhao⁵

Affiliations

¹ School of Environment and Chemical Engineering, Nanchang Hangkong University, Nanchang 330063, China; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
² Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: [email protected].
³ Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China.
⁴ School of Environment and Chemical Engineering, Nanchang Hangkong University, Nanchang 330063, China. Electronic address: [email protected].
⁵ Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: [email protected].

PMID: 28738649
DOI: 10.1016/j.talanta.2017.07.002

Abstract

Superparamagnetic core-shell molecularly imprinted polymer nanoparticles (MIPs) were prepared via surface initiated reversible-addition fragmentation chain transfer (si-RAFT) polymerization for the selective recognition of 2,4-dichlorophenoxyacetic acid (2,4-D) in real samples. The construction of uniform core-shell structure with a 50nm MIP layer was successfully accomplished, which favored mass transfer and resulted in fast recognition kinetics. The static equilibrium experiments revealed the satisfied adsorption capacity and imprinting efficiency of Fe₃O₄@MIP. Moreover, the Fe₃O₄@MIP exhibited high selectivity and affinity towards 2,4-D over structural analogues. The prepared Fe₃O₄@MIP nanoparticles were used for the selective enrichment of 2,4-D in tap water and Chinese cabbage samples. Combined with RP-HPLC, the recoveries of 2,4-D were calculated from 93.1% to 103.3% with RSD of 1.7-5.4% (n = 3) in Chinese cabbage samples. This work provides a versatile approach for fabricating well-constructed core-shell MIP nanoparticles for rapid enrichment and highly selective separation of target molecules in real samples.

Keywords: 2,4-dichlorophenoxyacetic acid; Chinese cabbage; Molecularly imprinted polymer; Reversible addition-fragmentation chain transfer polymerization; Superparamagnetic.