Assessment of strain and dyssynchrony in normal fetuses using speckle tracking echocardiography - comparison of three different ultrasound probes

J Perinat Med. 2018 Nov 27;46(9):960-967. doi: 10.1515/jpm-2017-0113.

Abstract

Objective: To evaluate segmental left (LV-S) and right (RV-S) ventricular strain as well as longitudinal mechanical myocardial dyssynchrony as a time difference between peaks in strain of both ventricles in fetuses (two-chamber-dyssynchrony, 2C-DYS) using speckle tracking echocardiography (STE). The aim of our study was to evaluate the influence of data acquisition on the results of STE measurement using different ultrasound probes.

Methods: We prospectively recorded cardiac cycles of four-chamber views of 56 normal fetuses with three different ultrasound probes and analyzed them offline with speckle tracking imaging software. Furthermore, we looked at a possible influence of heartbeat variability (beat-to-beat variability).

Results: The evaluation of the parameters was feasible with all three probes in 53 cases. There was no influence of heartbeat variability and no noticeable differences in 2C-DYS, LV-S and RV-S in all cases and for all three probes determined.

Conclusion: Assessment of strain and dyssynchrony using STE with three different probes is comparable. Further research is needed to validate dyssynchrony as a predictor for fetal outcome.

Keywords: Dyssynchrony; fetal; myocardial deformation; strain; two-dimensional speckle-tracking echocardiography.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Cardiovascular Physiological Phenomena*
  • Cardiovascular System / diagnostic imaging
  • Comparative Effectiveness Research
  • Echocardiography / methods*
  • Female
  • Fetus* / diagnostic imaging
  • Fetus* / physiology
  • Humans
  • Pregnancy
  • Reproducibility of Results
  • Ultrasonography, Prenatal / methods