Relationship between diminution of small pulmonary vessels and emphysema in chronic obstructive pulmonary disease

Clin Imaging. 2017 Nov-Dec:46:85-90. doi: 10.1016/j.clinimag.2017.07.008. Epub 2017 Jul 18.

Abstract

Objectives: To investigate the relationship between small pulmonary vessels and extent of emphysema on CT in individual lungs with chronic obstructive pulmonary disease (COPD).

Methods: Forty-nine patients were included. The percentage of cross-sectional area of vessels <5mm2 (%CSA <5) and extent of emphysema were assessed.

Results: Less than half of the COPD patients demonstrated an inverse correlation between %CSA <5 and percentage of low attenuation area (LAA%). In the remaining patients, %CSA <5 was homogeneously distributed.

Conclusion: Not all patients with COPD demonstrated an inverse correlation of the distributions between %CSA <5 and LAA% in individual lungs.

Keywords: COPD; CT scan cross-sectional area; Emphysema; Small pulmonary vessel.

MeSH terms

  • Aged
  • Blood Vessels / pathology*
  • Cross-Sectional Studies
  • Emphysema / etiology
  • Emphysema / pathology*
  • Female
  • Humans
  • Lung / blood supply
  • Lung / pathology*
  • Male
  • Middle Aged
  • Pulmonary Artery / pathology
  • Pulmonary Disease, Chronic Obstructive / pathology
  • Pulmonary Emphysema / pathology*
  • Pulmonary Veins / pathology
  • Tomography, X-Ray Computed