Burning Fat and Building Bone by FSH Blockade

Carlos Henrique Sponton; Shingo Kajimura

doi:10.1016/j.cmet.2017.07.018

Burning Fat and Building Bone by FSH Blockade

Cell Metab. 2017 Aug 1;26(2):285-287. doi: 10.1016/j.cmet.2017.07.018.

Authors

Carlos Henrique Sponton¹, Shingo Kajimura²

Affiliations

¹ Diabetes Center and Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, USA; Obesity and Comorbidities Research Center-OCRC, University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil.
² Diabetes Center and Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, USA. Electronic address: [email protected].

Abstract

The rise of follicle-stimulating hormone (FSH) is a hallmark of menopause associated with osteoporosis and visceral adiposity. In Nature, Zaidi and colleagues (Liu et al., 2017) report that blocking FSH action reduces body fat by promoting brown/beige fat thermogenesis, potentially providing a new intervention for the treatment of menopause-related metabolic diseases.

Publication types

Comment

MeSH terms

Adipose Tissue
Adipose Tissue, Beige
Bone and Bones
Female
Follicle Stimulating Hormone*
Humans
Thermogenesis*

Substances

Follicle Stimulating Hormone

Grants and funding

R01 DK097441/DK/NIDDK NIH HHS/United States