5,6,7,3',4',5'-Hexamethoxyflavone from the Australian plant Eremophila debilis (Myoporaceae)

Mark S Butler; Peter C Healy; Paul I Forster; Gordon P Guymer; Ronald J Quinn

doi:10.1016/j.fitote.2017.07.014

5,6,7,3',4',5'-Hexamethoxyflavone from the Australian plant Eremophila debilis (Myoporaceae)

Fitoterapia. 2018 Apr:126:90-92. doi: 10.1016/j.fitote.2017.07.014. Epub 2017 Aug 1.

Authors

Mark S Butler¹, Peter C Healy¹, Paul I Forster², Gordon P Guymer², Ronald J Quinn³

Affiliations

¹ Griffith Institute for Drug Discovery, Griffith University, Brisbane, Australia.
² Queensland Herbarium, Department of Science, Information Technology and Innovation, Brisbane Botanic Gardens, Toowong, Australia.
³ Griffith Institute for Drug Discovery, Griffith University, Brisbane, Australia. Electronic address: [email protected].

PMID: 28774690
DOI: 10.1016/j.fitote.2017.07.014

Abstract

The aerial parts of the endemic Australian plant Eremophila debilis (Myoporaceae) contain 3% dry weight of the biologically active 5,6,7,3',4',5'-hexamethoxyflavone, which had its structured confirmed using X-ray crystal crystallography. The presence of significant levels of the polypharmacologically active 5,6,7,3',4',5'-hexamethoxyflavone in the edible parts of the plant has potential implications for its use as a food and bush medicine.

Keywords: 5,6,7,3′,4′,5′-hexamethoxyflavone; Australia; Eremophila debilis; Myoporaceae.

MeSH terms

Eremophila Plant / chemistry*
Flavones / chemistry*
Flavones / isolation & purification
Molecular Structure
Plant Components, Aerial / chemistry
Queensland

Substances

Flavones
nobiletin