MMR-deficiency and BRCA2/EGFR/NTRK mutations

Aging (Albany NY). 2017 Aug 3;9(8):1849-1850. doi: 10.18632/aging.101275.
No abstract available

Keywords: BRCA2; CRC; EGFR; MSI-H; NTRK.

Publication types

  • Editorial

MeSH terms

  • Antibodies, Monoclonal, Humanized / therapeutic use
  • BRCA2 Protein / genetics*
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / genetics*
  • DNA Mismatch Repair / genetics*
  • ErbB Receptors / genetics
  • Humans
  • Microsatellite Instability*
  • Mutation
  • Receptor Protein-Tyrosine Kinases / genetics*

Substances

  • Antibodies, Monoclonal, Humanized
  • BRCA2 Protein
  • BRCA2 protein, human
  • pembrolizumab
  • EGFR protein, human
  • ErbB Receptors
  • Receptor Protein-Tyrosine Kinases