A variant of HLA-DRB111, HLA-DRB111:143, discovered in a Chinese hematopoietic stem cell donor

HLA. 2017 Nov;90(5):321-323. doi: 10.1111/tan.13116. Epub 2017 Sep 4.

Authors

X-F Li^{1

2

3}, G-J Li⁴, X Zhang^{1

2}, H Fan⁴, J-P Li^{1

2

3

5}

Affiliations

¹ HLA Laboratory, Liaoning Blood Center, Shenyang, China.
² Key Laboratory of Blood Safety Research of Liaoning, Shenyang, China.
³ Shenyang Research Center for Cell Application, Shenyang, China.
⁴ Department of Hematology, Forth Affiliated Hospital of China Medical University, Shenyang, China.
⁵ Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.

PMID: 28796435
DOI: 10.1111/tan.13116

Abstract

HLA-DRB1*11:143 has one nucleotide change from HLA-DRB1*11:01:01 where Aspartic Acid (70) is changed to Glycine.

Keywords: HLA-DRB1*11:143; novel allele; sequence-based typing.

© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Amino Acid Sequence
Asian People / genetics*
Base Sequence
Exons / genetics
HLA-DRB1 Chains / chemistry
HLA-DRB1 Chains / genetics*
Hematopoietic Stem Cells / metabolism*
Histocompatibility Testing
Humans
Tissue Donors*

Substances

HLA-DRB1 Chains