Human Metapneumovirus Infection and Acute Respiratory Distress Syndrome During Pregnancy

Obstet Gynecol. 2017 Sep;130(3):630-632. doi: 10.1097/AOG.0000000000002165.

Abstract

Background: Human metapneumovirus has recently been recognized as an important cause of severe respiratory viral infections and of viral infections in patients admitted to intensive care units. Little is known about the course of this infection in pregnancy.

Case: A late-preterm primigravid woman was admitted to the intensive care unit for acute respiratory distress syndrome and subsequently diagnosed with human metapneumovirus. Because of worsening maternal respiratory status, she was intubated and a primary cesarean delivery was performed. The patient's respiratory status continued to decline postpartum, and she ultimately required extracorporeal membrane oxygenation. She was treated supportively until her respiratory status improved, at which time she was extubated and weaned off extracorporeal membrane oxygenation and subsequently discharged home.

Conclusion: Human metapneumovirus can lead to severe respiratory illness during pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Cesarean Section
  • Diagnosis, Differential
  • Female
  • Humans
  • Infant, Newborn
  • Metapneumovirus / isolation & purification*
  • Paramyxoviridae Infections / diagnosis*
  • Paramyxoviridae Infections / diagnostic imaging
  • Paramyxoviridae Infections / drug therapy
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • Pregnancy Complications, Infectious / diagnostic imaging
  • Pregnancy Complications, Infectious / drug therapy
  • Prenatal Diagnosis
  • Respiratory Distress Syndrome / diagnosis*
  • Respiratory Distress Syndrome / diagnostic imaging
  • Respiratory Distress Syndrome / drug therapy