Primary Cutaneous B-cell Lymphomas

Charity B Hope; Laura B Pincus

doi:10.1016/j.cll.2017.05.009

Primary Cutaneous B-cell Lymphomas

Clin Lab Med. 2017 Sep;37(3):547-574. doi: 10.1016/j.cll.2017.05.009.

Authors

Charity B Hope¹, Laura B Pincus²

Affiliations

¹ Department of Pathology, UCSF Dermatopathology Section, University of California, San Francisco, 1701 Divisidero Street, Room 280, San Francisco, CA 94115, USA.
² Department of Pathology, UCSF Dermatopathology Section, University of California, San Francisco, 1701 Divisidero Street, Room 280, San Francisco, CA 94115, USA; Department of Dermatology, UCSF Dermatopathology Section, University of California, San Francisco, 1701 Divisidero Street, Room 280, San Francisco, CA 94115, USA. Electronic address: [email protected].

PMID: 28802500
DOI: 10.1016/j.cll.2017.05.009

Abstract

B-cell lymphomas represent approximately 20% to 25% of primary cutaneous lymphomas. Within this group, most cases (>99%) are encompassed by 3 diagnostic entities: primary cutaneous marginal zone lymphoma, primary cutaneous follicle center lymphoma, and primary cutaneous diffuse large B-cell lymphoma, leg type. In this article, the authors present clinical, histopathologic, immunophenotypic, and molecular features of each of these entities and briefly discuss the rarer intravascular large B-cell lymphoma.

Keywords: Intravascular diffuse large B-cell lymphoma; Leg type; Primary cutaneous B-cell lymphoma; Primary cutaneous diffuse large B-cell lymphoma; Primary cutaneous follicle center lymphoma; Primary cutaneous marginal zone lymphoma.

Publication types

Review

MeSH terms

Humans
Immunophenotyping
Lymphoma, B-Cell / immunology
Lymphoma, B-Cell / pathology*
Lymphoma, Follicular / immunology
Lymphoma, Follicular / pathology*
Lymphoma, Large B-Cell, Diffuse / immunology
Lymphoma, Large B-Cell, Diffuse / pathology
Skin Neoplasms / immunology
Skin Neoplasms / pathology*