Cardiac neuroanatomy - Imaging nerves to define functional control

Peter Hanna; Pradeep S Rajendran; Olujimi A Ajijola; Marmar Vaseghi; J Andrew Armour; Jefrrey L Ardell; Kalyanam Shivkumar

doi:10.1016/j.autneu.2017.07.008

Cardiac neuroanatomy - Imaging nerves to define functional control

Auton Neurosci. 2017 Nov:207:48-58. doi: 10.1016/j.autneu.2017.07.008. Epub 2017 Jul 29.

Authors

Peter Hanna¹, Pradeep S Rajendran², Olujimi A Ajijola¹, Marmar Vaseghi¹, J Andrew Armour¹, Jefrrey L Ardell², Kalyanam Shivkumar³

Affiliations

¹ University of California Los Angeles (UCLA) Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
² University of California Los Angeles (UCLA) Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; Molecular, Cellular & Integrative Physiology Program, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
³ University of California Los Angeles (UCLA) Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; Molecular, Cellular & Integrative Physiology Program, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. Electronic address: [email protected].

Abstract

The autonomic nervous system regulates normal cardiovascular function and plays a critical role in the pathophysiology of cardiovascular disease. Further understanding of the interplay between the autonomic nervous system and cardiovascular system holds promise for the development of neuroscience-based cardiovascular therapeutics. To this end, techniques to image myocardial innervation will help provide a basis for understanding the fundamental underpinnings of cardiac neural control. In this review, we detail the evolution of gross and microscopic anatomical studies for functional mapping of cardiac neuroanatomy.

Keywords: Autonomic nervous system; Intracardiac nervous system; Myocardial innervation; Neurocardiology.

Publication types

Review

MeSH terms

Autonomic Nervous System / physiopathology*
Cardiovascular Diseases / physiopathology
Heart / innervation*
Humans
Image Processing, Computer-Assisted* / methods
Motor Neurons / physiology
Neuroanatomy* / methods

Abstract

Publication types

MeSH terms

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