The evolution of paroxysmal nocturnal haemoglobinuria depends on intensity of immunosuppressive therapy

Br J Haematol. 2018 Sep;182(5):730-733. doi: 10.1111/bjh.14862. Epub 2017 Aug 14.

Authors

Taha Bat¹, Omnia N Abdelhamid¹, Suresh K Balasubramanian¹, Aly Mai¹, Tomas Radivoyevitch², Michael Clemente¹, Jaroslaw P Maciejewski¹

Affiliations

¹ Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
² Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

No abstract available

Keywords: aplastic anaemia; clonal evolution; immunosuppressive therapy; paroxysmal nocturnal haemoglobinuria.

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Anemia, Aplastic / diagnosis
Anemia, Aplastic / pathology*
Cell Proliferation
Cell Size
Clone Cells / pathology
Disease Progression
Hemoglobinuria, Paroxysmal / diagnosis
Hemoglobinuria, Paroxysmal / drug therapy
Hemoglobinuria, Paroxysmal / etiology*
Humans
Immunosuppression Therapy / methods*
Middle Aged
Myelodysplastic Syndromes
Retrospective Studies

Grants and funding