Patient, caregiver, and provider perceptions of pain and pain management in adolescents and young adults with bleeding disorders

Haemophilia. 2017 Nov;23(6):852-860. doi: 10.1111/hae.13293. Epub 2017 Aug 14.

Abstract

Introduction: Recurrent bleeding and associated pain are critical components in the management of bleeding disorders, yet scant data describe perceptions of pain in this patient population.

Objective: This study assessed perceptions of pain and pain management in adolescents and young adults (AYAs) with haemophilia or von Willebrand disease (VWD) to determine agreement/disagreement between patients, caregivers and health care providers.

Methods: Using an online questionnaire, AYA patients (N=89), their caregivers (N=77), and providers (N=54) reported on pain perception, pain treatment and pain control. Acute and chronic pain was measured in patients via the Faces Pain Scale-Revised (FPS-R). Questionnaires queried about pharmacologic and non-pharmacologic pain management methods and how well providers and caregivers helped to manage pain.

Results: Poor agreement existed between patients and caregivers across all pain levels, perception of pain control and effectiveness of pain management. Specifically for chronic pain, poor agreement was noted between patients and caregivers (kappa=0.04; 29% agreement) and patients and providers (kappa=-0.07; 21.4% agreement). Among patients reporting acute or chronic pain, only 67% and 43%, respectively, utilized medication for their specific pain. Patients used more opioid medications than expected by their providers. On average, AYAs reported initial use of pain medications for chronic pain at 11.5 years.

Conclusions: Ongoing research is needed in haemophilia and VWD pain management, and on the differences in pain perception between patients, caregivers and providers. As chronic pain often begins at an early age, optimal pain management should include acknowledging patient complaints, exploring pharmacologic and non-pharmacologic options, and optimizing prophylaxis.

Keywords: acute pain; chronic pain; haemophilia; non-pharmacologic treatment; opioids; von Willebrand disease.

MeSH terms

  • Adolescent
  • Adult
  • Analgesics, Opioid / therapeutic use
  • Caregivers / psychology
  • Caregivers / statistics & numerical data*
  • Female
  • Health Personnel / psychology
  • Health Personnel / statistics & numerical data*
  • Hemophilia A / drug therapy
  • Hemophilia A / physiopathology*
  • Hemophilia A / psychology
  • Humans
  • Male
  • Pain / physiopathology
  • Pain / psychology
  • Pain Management / methods
  • Pain Measurement
  • Pain Perception*
  • Patients / psychology
  • Patients / statistics & numerical data*
  • Quality of Life
  • Surveys and Questionnaires
  • Young Adult
  • von Willebrand Diseases / drug therapy
  • von Willebrand Diseases / physiopathology*
  • von Willebrand Diseases / psychology

Substances

  • Analgesics, Opioid