Cytogenetic studies on patients with medullary carcinoma of the thyroid

Cancer Genet Cytogenet. 1987 Apr;25(2):303-7. doi: 10.1016/0165-4608(87)90191-9.

Abstract

Cytogenetic studies were carried out on stimulated lymphocyte cultures of patients with medullary carcinoma of the thyroid. Of 32 patients studied, seven had a hereditary carcinoma, and five had multiple endocrine neoplasia type 2A and two had type 2B. Neither a constitutional chromosome abnormality nor an increase in chromosomal breakage were detected in these patients.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Carcinoma / genetics*
  • Chromosome Aberrations*
  • Female
  • Humans
  • Karyotyping
  • Male
  • Middle Aged
  • Multiple Endocrine Neoplasia / genetics*
  • Thyroid Neoplasms / genetics*