Highly efficient and precise base editing in discarded human tripronuclear embryos

Protein Cell. 2017 Oct;8(10):776-779. doi: 10.1007/s13238-017-0458-7.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • CRISPR-Cas Systems*
  • Embryo, Mammalian*
  • Gene Editing / methods*
  • HEK293 Cells
  • Humans
  • Polycomb Repressive Complex 1 / genetics*
  • Zygote*

Substances

  • Polycomb Repressive Complex 1
  • RNF2 protein, human