High mortality rate associated with KPC-producing Enterobacter cloacae in a Brazilian hospital

Am J Infect Control. 2018 Jan;46(1):108-110. doi: 10.1016/j.ajic.2017.07.011. Epub 2017 Aug 23.

Abstract

We describe a clonal dissemination of KPC-producing Enterobacter cloacae in a Brazilian hospital. Patients diagnosed with theses isolates showed high mortality rate (41.8%) and were associated with previous use of antibiotics and urinary catheterization. Therefore, infection control measures and use of stricter antibiotic policies are required to control the spread of these organisms.

Keywords: Antibiotic resistance; Enterobacteriaceae; β-lactamases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brazil / epidemiology
  • Enterobacter cloacae / metabolism*
  • Enterobacteriaceae Infections / epidemiology
  • Enterobacteriaceae Infections / microbiology*
  • Enterobacteriaceae Infections / mortality*
  • Gene Expression Regulation, Bacterial / physiology*
  • Gene Expression Regulation, Enzymologic / physiology*
  • Humans
  • beta-Lactamases / genetics
  • beta-Lactamases / metabolism*

Substances

  • beta-Lactamases