Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures
Nat Genet
.
2017 Aug 30;49(9):1289-1291.
doi: 10.1038/ng.3877.
Authors
Marc J Williams
1
2
3
,
Benjamin Werner
4
,
Chris P Barnes
2
5
,
Trevor A Graham
1
,
Andrea Sottoriva
4
Affiliations
1
Evolution and Cancer Laboratory, Barts Cancer Institute, Queen Marry University of London, London, UK.
2
Department of Cell and Developmental Biology, University College London, London, UK.
3
Centre for Mathematics and Physics in the Life Sciences and Experimental Biology (CoMPLEX), University College London, London, UK.
4
Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.
5
Department of Genetics, Evolution and Environment, University College London, London, UK.
PMID:
28854180
DOI:
10.1038/ng.3877
No abstract available
Publication types
Comment
MeSH terms
Biological Evolution*
Gene Frequency
Humans
Neoplasms*
Grants and funding
097319/WT_/Wellcome Trust/United Kingdom
19771/CRUK_/Cancer Research UK/United Kingdom
22909/CRUK_/Cancer Research UK/United Kingdom