[Radiotherapy for head and neck squamous cell carcinoma: State of the art and future directions]

Cancer Radiother. 2017 Oct;21(6-7):498-504. doi: 10.1016/j.canrad.2017.07.032. Epub 2017 Aug 31.
[Article in French]

Abstract

Therapeutic principles of radiation therapy in head and neck carcinomas will be discussed in this review. Intensity-modulated radiotherapy with concomitant cisplatin should be standard. In case of contraindication to chemotherapy, cetuximab is an option, while hyperfractionation should be considered in patients unfit for concomitant treatment. Concomitant chemotherapy should be administered in the presence of extracapsular extensions and positive margins in the postoperative setting. Current research areas such as desescalation in human papillomavirus-positive tumours, adaptive radiotherapy, radiomics and immunotherapy will also be addressed.

Keywords: Actualités; Head and neck; ORL; Radiotherapy; Radiothérapie; State of the art; État de l’art.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / radiotherapy*
  • Carcinoma, Squamous Cell / surgery
  • Chemoradiotherapy
  • Combined Modality Therapy
  • Forecasting
  • Head and Neck Neoplasms / drug therapy
  • Head and Neck Neoplasms / radiotherapy*
  • Head and Neck Neoplasms / surgery
  • Humans
  • Precision Medicine
  • Radiotherapy / trends
  • Squamous Cell Carcinoma of Head and Neck