Carcinoma-in-situ testis in patients with assumed extragonadal germ-cell tumours

Lancet. 1987 Sep 5;2(8558):528-30. doi: 10.1016/s0140-6736(87)92922-9.

Abstract

Testicular biopsies were done in 15 consecutive patients who were believed to have extragonadal germ-cell tumours. 8 patients (53%) had carcinoma-in-situ (CIS) in the gonads, although none had clinical signs of tumour. In addition, 3 of these patients had small areas of invasive tumour growth. Germ-cell tumours can only be diagnosed as being extragonadal in origin if testicular biopsy appearances are normal.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Biopsy
  • Carcinoma in Situ / diagnosis*
  • Carcinoma in Situ / pathology
  • Dysgerminoma / diagnosis
  • Dysgerminoma / pathology
  • Humans
  • Male
  • Mediastinal Neoplasms / diagnosis*
  • Mediastinal Neoplasms / pathology
  • Middle Aged
  • Neoplasms, Germ Cell and Embryonal / diagnosis*
  • Neoplasms, Germ Cell and Embryonal / pathology
  • Neoplasms, Germ Cell and Embryonal / secondary
  • Retroperitoneal Neoplasms / diagnosis*
  • Retroperitoneal Neoplasms / pathology
  • Testicular Neoplasms / diagnosis*
  • Testicular Neoplasms / pathology