Abstract
A fungal protease (Alp1/Asp f13) from Aspergillus fumigatus was detected in the airways of subjects with asthma but not controls, which correlated strongly with disease severity, respiratory dysfunction, and steroid use.
Publication types
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Letter
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Research Support, N.I.H., Intramural
MeSH terms
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Allergens / immunology
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Aspergillus fumigatus / enzymology
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Aspergillus fumigatus / immunology*
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Asthma / diagnosis*
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Asthma / immunology*
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Bacterial Proteins / immunology*
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Endopeptidases / immunology*
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Humans
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Respiratory Mucosa / immunology
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Respiratory Mucosa / microbiology
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Respiratory Mucosa / pathology
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Severity of Illness Index
Substances
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Allergens
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Bacterial Proteins
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Endopeptidases
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alkaline protease