Indocyanine green fluorescence imaging in colorectal surgery: overview, applications, and future directions

Lancet Gastroenterol Hepatol. 2017 Oct;2(10):757-766. doi: 10.1016/S2468-1253(17)30216-9.

Abstract

Indocyanine green fluorescence imaging is a surgical tool with increasing applications in colorectal surgery. This tool has received acceptance in various surgical disciplines as a potential method to enhance surgical field visualisation, improve lymph node retrieval, and decrease the incidence of anastomotic leaks. In colorectal surgery specifically, small studies have shown that intraoperative fluorescence imaging is a safe and feasible method to assess anastomotic perfusion, and its use might affect the incidence of anastomotic leaks. Controlled trials are ongoing to validate these conclusions. The number of new indications for indocyanine green continues to increase, including innovative options for detecting and guiding management of colorectal metastasis to the liver. These advances could offer great value for surgeons and patients, by improving the accuracy and outcomes of oncological resections.

Publication types

  • Review

MeSH terms

  • Anastomosis, Surgical / adverse effects
  • Colorectal Neoplasms / diagnostic imaging*
  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / surgery*
  • Coloring Agents*
  • Fluorescein Angiography*
  • Humans
  • Indocyanine Green*
  • Intraoperative Complications / prevention & control
  • Intraoperative Period
  • Liver Neoplasms / secondary
  • Lymphatic Metastasis
  • Peritoneal Neoplasms / secondary
  • Sentinel Lymph Node / diagnostic imaging
  • Sentinel Lymph Node / pathology

Substances

  • Coloring Agents
  • Indocyanine Green