Drivers of Dengue Intrahost Evolution

Etienne Simon-Lorière; Marco Vignuzzi

doi:10.1016/j.chom.2017.08.015

Drivers of Dengue Intrahost Evolution

Cell Host Microbe. 2017 Sep 13;22(3):260-261. doi: 10.1016/j.chom.2017.08.015.

Authors

Etienne Simon-Lorière¹, Marco Vignuzzi²

Affiliations

¹ Functional Genetics of Infectious Diseases Unit, Institut Pasteur, 75015 Paris, France; CNRS, URA 3012, 75015 Paris, France.
² Viral Populations and Pathogenesis Unit, Institut Pasteur, 75015 Paris, France; CNRS UMR 3569, 75015 Paris, France. Electronic address: [email protected].

PMID: 28910632
DOI: 10.1016/j.chom.2017.08.015

Abstract

RNA viruses circulate as rapidly evolving swarms of related variants, and their evolutionary dynamics within hosts may be key to understanding virus emergence. In this issue of Cell Host & Microbe, Parameswaran et al. (2017) combine next-generation sequencing and functional studies to characterize viral populations in acute dengue infections.

Publication types

Comment

MeSH terms

Dengue / virology*
Evolution, Molecular*
High-Throughput Nucleotide Sequencing
RNA Viruses