ZnO nanotubes supported molecularly imprinted polymers arrays as sensing materials for electrochemical detection of dopamine

Talanta. 2018 Jan 1:176:573-581. doi: 10.1016/j.talanta.2017.08.083. Epub 2017 Aug 29.

Abstract

In this study, ZnO nanotubes (ZNTs) were prepared onto fluorine-doped tin oxide (FTO) glass and used as supports for MIPs arrays fabrication. Due to the imprinted cavities are always located at both inner and outer surface of ZNTs, these ZNTs supported MIPs arrays have good accessibility towards template and can be used as sensing materials for chemical sensors with high sensitivity, excellent selectivity and fast response. Using K3[Fe(CN)6] as electron probe, the fabricated electrochemical sensor shows two linear dynamic ranges (0.02-5μM and 10-800μM) towards dopamine. This proposed electrochemical sensor has been applied for dopamine determination with satisfied recoveries and precision. More complex human urine samples also confirmed that the proposed method has good accuracy for dopamine determination in real biological samples. These results suggest potential applicability of the proposed method and sensor in important molecule analysis.

Keywords: Arrays; Dopamine; Electrochemical sensor; Molecularly imprinted polymers (MIPs); ZnO nanotubes (ZNTs).

MeSH terms

  • Dopamine / analysis*
  • Dopamine / chemistry
  • Dopamine / urine
  • Electrochemical Techniques
  • Fluorine / chemistry
  • Glass / chemistry
  • Humans
  • Molecular Imprinting*
  • Nanotubes / chemistry*
  • Polymers / chemistry*
  • Tin Compounds / chemistry
  • Zinc Oxide / chemistry*

Substances

  • Polymers
  • Tin Compounds
  • Fluorine
  • stannic oxide
  • Zinc Oxide
  • Dopamine