Abstract
A new sesquiterpene kalinturoside A (1), and 17 known compounds friedelan-3-ol (2), 24-ethyl-5a-cholesta-7, 22(E)-dien-3-one (3), friedelin (4), syringaresinol (5), α-spinasterol (6), ciwujiatone (7), syringic acid (8), scopoletin (9), apocynin (10), 1-(3-hydroxy-4, 5-dimethoxyphenyl)ethan-1-one (11), apigenin (12), 5-hydroxymethylfurfural (13), stigmasterol-3-O-β-d-glucopy-ranoside (14), bidenoside C (15), citrusin (16), irioresinol A (17) and syringaresinol-4-O-β-d-glucopyranoside (18) were isolated from the herbs of Kalimeris integrifolia. The structures of these compounds were elucidated using spectroscopic techniques such as NMR and MS. All of the compounds were isolated from this genus for the first time.
Keywords:
Kalimeris integrifolia; cytotoxic activity; kalinturoside A; sesquiterpene.
MeSH terms
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Alkynes / chemistry
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Alkynes / pharmacology
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Antineoplastic Agents, Phytogenic / chemistry*
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Antineoplastic Agents, Phytogenic / pharmacology*
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Asteraceae / chemistry*
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Cell Line, Tumor
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry
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Furaldehyde / analogs & derivatives
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Furaldehyde / chemistry
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Furaldehyde / pharmacology
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Furans / chemistry
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Furans / pharmacology
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Glucosides / chemistry
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Glucosides / pharmacology
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Humans
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Lignans / chemistry
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Lignans / pharmacology
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Sesquiterpenes / chemistry*
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Sesquiterpenes / pharmacology
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Stigmasterol / analogs & derivatives
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Stigmasterol / chemistry
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Stigmasterol / pharmacology
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Triterpenes / chemistry
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Triterpenes / pharmacology
Substances
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Alkynes
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Antineoplastic Agents, Phytogenic
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Drugs, Chinese Herbal
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Furans
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Glucosides
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Lignans
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Sesquiterpenes
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Triterpenes
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bidenoside C
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friedelan-3-ol
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syringaresinol-4''-O-glucoside
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spinasterol
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syringaresinol
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5-hydroxymethylfurfural
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Stigmasterol
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friedelin
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Furaldehyde