Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil

Emerg Infect Dis. 2017 Oct;23(10):1737-1739. doi: 10.3201/eid2310.161855.

Abstract

We isolated East/Central/South African genotype chikungunya virus during the 2016 epidemic in Rio de Janeiro, Brazil. Genome sequencing revealed unique mutations in the nonstructural protein 4 (NSP4-A481D) and envelope protein 1 (E1-K211T). Moreover, all Brazil East/Central/South isolates shared the exclusive mutations E1-M407L and E2-A103T.

Keywords: Brazil; Chikungunya virus; ECSA genotype; East/Central/South African Genotype; Zika virus; alphaviruses; arboviruses; dengue virus; mosquitoes; vector-borne infections; viruses.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aedes / virology*
  • Africa / epidemiology
  • Animals
  • Brazil / epidemiology
  • Chikungunya Fever / epidemiology*
  • Chikungunya Fever / transmission*
  • Chikungunya Fever / virology
  • Chikungunya virus / classification
  • Chikungunya virus / genetics*
  • Chikungunya virus / isolation & purification
  • Chlorocebus aethiops
  • Female
  • Genotype
  • Humans
  • Insect Vectors / virology*
  • Male
  • Phylogeny
  • RNA, Viral / genetics*
  • Vero Cells

Substances

  • RNA, Viral