Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL

Leukemia. 2018 Jan;32(1):234-236. doi: 10.1038/leu.2017.274. Epub 2017 Aug 29.

Authors

K Brazdilova^{1

2}, K Plevova^{1

2}, H Skuhrova Francova¹, H Kockova^{1

2}, M Borsky¹, V Bikos², J Malcikova^{1

2}, A Oltova¹, J Kotaskova^{1

2}, B Tichy², Y Brychtova¹, J Mayer^{1

2}, M Doubek^{1

2}, S Pospisilova^{1

2}

Affiliations

¹ Department of Internal Medicine-Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic.
² Center of Molecular Medicine, CEITEC - Central European Institute of Technology, Masaryk University, Brno, Czech Republic.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

B-Lymphocytes / metabolism
Gene Rearrangement, B-Lymphocyte, Heavy Chain / genetics*
Humans
Immunoglobulin Heavy Chains / genetics*
Immunophenotyping / methods
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*

Substances

Immunoglobulin Heavy Chains