APOL1 and blood pressure changes in young adults

Girish N Nadkarni; Steven G Coca

doi:10.1016/j.kint.2017.05.030

APOL1 and blood pressure changes in young adults

Kidney Int. 2017 Oct;92(4):793-795. doi: 10.1016/j.kint.2017.05.030.

Authors

Girish N Nadkarni¹, Steven G Coca²

Affiliations

¹ Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: [email protected].
² Mount Sinai Hospital, New York, New York, USA.

PMID: 28938952
DOI: 10.1016/j.kint.2017.05.030

Abstract

APOL1 risk variants have been shown to be associated with kidney disease and hypertension. In this study, Chen and colleagues assess the association of these risk variants with longitudinal blood pressure in young adults. We review the current literature on association of these alleles with blood pressure and propose future directions to resolve the existing controversies.

Publication types

Comment

MeSH terms

Adult
Apolipoprotein L1
Apolipoproteins / genetics*
Black or African American
Blood Pressure*
Genetic Predisposition to Disease
Humans
Lipoproteins, HDL / genetics
Risk Factors
Young Adult

Substances

APOL1 protein, human
Apolipoprotein L1
Apolipoproteins
Lipoproteins, HDL

Abstract

Publication types

MeSH terms

Substances

Grants and funding