Background: Streptococcus pneumoniae is the main etiology of community-acquired pneumonia (CAP). A quick detection of urinary antigen helps in obtaining a documented result in case of Streptococcus pneumoniae CAP.
Methods: We compared the BinaxNOW®S. pneumoniae test with the new urinary antigen Sofia®S. pneumoniae FIA. We examined 133 urine samples.
Results: Of the 133 included and tested non-concentrated urine samples, BinaxNOW® and Sofia® tests yielded 122 and 113 negative results and 11 and 20 positive results, respectively. The overall agreement between the tests was good.
Conclusion: This new test enabled the diagnosis of seven additional cases (7/133=5.2%). The improved detection with Sofia® may be due to the immunofluorescence method used by this new test as compared with the colorimetric method used by BinaxNOW®. Sofia® also offers the advantage of being connected to the laboratory information system (LIS) allowing an automated traceability.
Keywords: BinaxNOW(®); Sofia(®); Streptococcus pneumoniae.
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