Levels of acrylamide in foods included in 'the first French total diet study on infants and toddlers'

Food Chem. 2018 Feb 1:240:997-1004. doi: 10.1016/j.foodchem.2017.08.035. Epub 2017 Aug 12.

Abstract

This study describes an optimisation and validation process using liquid chromatography coupled with tandem mass spectrometry to quantify acrylamide in foods mainly consumed by infants and toddlers. A limit of quantification of 5µg.kg-1 for both solid and liquid samples was achieved, except for unprepared infant cereals (LOQ of 18µg.kg-1). The method was then applied to 141 food samples from the first French total diet study on infants and toddlers. Acrylamide was detected in most samples at mean LB/UB concentrations ranging from 0.14 to 102µg.kg-1. The "Follow-on formula" and "Infant formula" products contained the lowest average content (LB/UB of 0.14/2.2µg.kg-1 and 0.60/2.9µg.kg-1 respectively) and the "Sweet and savoury biscuits and bars" (102µg.kg-1; n=1 represented by a plain dry biscuit) contained the highest.

Keywords: Acrylamide; Acrylamide (PubChem CID: 6579); Foods; Infants and toddlers; LC-MS/MS; Method validation; Total diet study.

MeSH terms

  • Acrylamide / analysis*
  • Chromatography, Liquid
  • Diet*
  • Edible Grain
  • Tandem Mass Spectrometry

Substances

  • Acrylamide