Restriction fragment length polymorphism in Felty's syndrome

D M Sansom; J L Bidwell; P T Klouda; P J Maddison

Restriction fragment length polymorphism in Felty's syndrome

Dis Markers. 1986 Jun;4(1-2):185-9.

Authors

D M Sansom¹, J L Bidwell, P T Klouda, P J Maddison

Affiliation

¹ United Kingdom Transplant Service, Bristol.

PMID: 2898315

Abstract

Southern blot analysis with DR beta and DQ beta cDNA probes was used to compare genomic DNA from Felty's syndrome patients with HLA-DR-matched normal controls. We describe two restriction fragment length polymorphisms putatively associated with Felty's syndrome.

MeSH terms

DNA / analysis
DNA / genetics
Felty Syndrome / genetics*
Felty Syndrome / immunology
Genetic Markers*
HLA-D Antigens / genetics*
HLA-DQ Antigens / genetics*
HLA-DR Antigens / genetics*
Humans
Polymorphism, Genetic*
Polymorphism, Restriction Fragment Length*

Substances

Genetic Markers
HLA-D Antigens
HLA-DQ Antigens
HLA-DR Antigens
DNA