Most elderly lack a synchronized circadian rhythm and often cannot benefit from light therapy. Non-visual effects of light are mediated through intrinsic photosensitive retinal ganglion cells (ipRGCs). With chromatic pupillometry, the functionality of ipRGCs and their functional circuit in the brain can be tested.
Keywords: circadian; dementia; intrinsic photosensitive retinal ganglion cells (ipRGCs); pupil; reflex.
© 2017 The Institute of Psychology, Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.