Characterization of Artifacts Associated With Multicolor Confocal Scanning Laser Ophthalmoscopy

Ophthalmic Surg Lasers Imaging Retina. 2017 Oct 1;48(10):810-815. doi: 10.3928/23258160-20170928-05.

Abstract

Background and objective: To characterize the appearance of three types of artifacts observed on multicolor confocal scanning laser ophthalmoscopy (cSLO).

Patients and methods: Retrospective review of 159 eyes of 96 consecutive patients from the Duke Eye Center who underwent multicolor cSLO with spectral-domain optical coherence tomography (SD-OCT). Infrared (IR), green, blue, and multicolor reflectance images were evaluated for artifacts with corresponding SD-OCT scans available for reference.

Results: Multicolor cSLO artifacts were detected in 23.3% (37 of 159) of eyes and comprised three main patterns: spot, wisp, and net. Only three instances of these artifacts were detected on IR reflectance versus 34, 37, and 35 instances on green, blue, and multicolor reflectance, respectively. Artifacts were observed in 0% of eyes with clear lenses, 27.7% of eyes with cataracts, and in 20.8% of eyes with posterior chamber intraocular lenses.

Conclusion: Awareness of spot, wisp, and net artifacts when interpreting multicolor cSLO images may facilitate the identification of true retinal pathology. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:810-815.].

MeSH terms

  • Artifacts*
  • Fundus Oculi
  • Humans
  • Microscopy, Confocal / methods*
  • Microscopy, Confocal / standards
  • Ophthalmoscopy / methods*
  • Ophthalmoscopy / standards
  • Optic Nerve Diseases / diagnostic imaging*
  • Retinal Diseases / diagnostic imaging*
  • Retrospective Studies
  • Tomography, Optical Coherence / methods